醫學研究
尤振霖 Chen-Lin Yu
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現職
新竹馬偕紀念醫院醫學研究科 資深助研究員
聯絡方式
電子信箱: [email protected]
院內分機: 5522-204
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主要學歷
中山醫學大學醫學研究所 博士 (2014-2020)
中山醫學大學醫學檢驗暨生物技術學系 碩士 (2012-2014)
中山醫學大學醫學檢驗暨生物技術學系 學士 (2008-2012)
主要經歷
馬偕醫學院生物醫學研究所 博士後研究員 (2020-2024)
執行項目或專長
MAJOR SERVICE
癌症分子醫學、腫瘤生物學、細胞藥理學
期刊論文
Chen-Lin Yu, Kai-Yao Huang, Jih-Jung Chen, Cheng-Ta Lai, Guang-Wei Chen, Chen-Chen Huang, Yen-Hsiu Yeh, Chien-Hsing Lee, Jie-Jen Lee, Dong-Ming Huang, Shih-Wei Wang. Hernandonine-mediated autophagic cell death in hepatocellular carcinoma: Interplay of p53 and YAP signaling pathways. Free Radical Biology and Medicine. 2024 Jun, 222, 456-466. (2023 IF: 7.1; Q1, 35/313 in BIOCHEMISTRY & MOLECULAR BIOLOGY; Q1, 15/186 in ENDOCRINOLOGY & METABOLISM).
Chen-Lin Yu, Yu-Wei Lai, Jih-Jung Chen, Jie-Jen Lee, Tsung-Hsien Chou, Chen-Chen Huang, Shih-Chia Liu, Guang-Wei Chen, Chung-Hsin Tsai, Shih-Wei Wang. Cryptocaryone induces apoptosis in human hepatocellular carcinoma cells by inhibiting aerobic glycolysis through Akt and c-Src signaling pathways. Journal of Food and Drug Analysis. 2023 Dec, 31(4):10. (2023 IF: 2.6; Q2, 85/173 in FOOD SCIENCE & TECHNOLOGY; Q2, 173/354 in PHARMACOLOGY & PHARMACY)
Yu-Ching Huang, Wei-Cheng Chen, Chen-Lin Yu, Ting-Kuo Chang, Augusta I-Chin Wei, Tsung-Ming Chang, Ju-Fang Liu, Shih-Wei Wang. FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression. Biochemical pharmacology. 2023 Dec, 218:115853. (2023 IF: 5.3; Q1, 34/354 in PHARMACOLOGY & PHARMACY)
Wen-Chun Sun, Chia-Liang Lin, Tzong-Huei Lee, Chia-Hao Chang, Ann-Zhi Ong, Yen-Hsiu Yeh, Chen-Lin Yu, Guang-Wei Chen, Yi-Hsien Hsieh, Shih-Wei Wang. Critical role of heme oxygenase-1 in chaetoglobosin A by triggering reactive oxygen species mediated mitochondrial apoptosis in colorectal cancer. Free radical biology & medicine. 2023 Nov, 208:833-845. (2023 IF: 7.1; Q1, 35/313 in BIOCHEMISTRY & MOLECULAR BIOLOGY; Q1, 15/186 in ENDOCRINOLOGY & METABOLISM)
Chen-Lin Yu, Hsiang-Lin Lee, Shun-Fa Yang, Shih-Wei Wang, Ching-Pin Lin, Yi-Hsien Hsieh, Hui-Ling Chiou. Protodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression. Journal of hepatocellular carcinoma. 2022 Apr, 9, 327-341. (2023 IF: 4.2; Q2, 89/322 in ONCOLOGY)
Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo. Anti-lymphangiogenic diterpenes from the bark of Calocedrus macrolepis var. formosana. Journal of Food and Drug Analysis. 2021 Dec, 29(4),5. (2023 IF: 2.6; Q2, 85/173 in FOOD SCIENCE & TECHNOLOGY; Q2, 173/354 in PHARMACOLOGY & PHARMACY)
Szu Lee , Shih-Wei Wang, Chen-Lin Yu, Huai-Ching Tai, Juei-Yu Yen, Yu-Lien Tuan, Hsueh-Hsiao Wang, Yi-Ting Liu, Shiou-Sheng Chen, Hsueh-Yun Lee. Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2 Bioorganic & medicinal chemistry. 2021, Nov, 50: 116454. (2023 IF: 3.3; Q2, 149/313 in BIOCHEMISTRY & MOLECULAR BIOLOGY; Q2, 36/72 in CHEMISTRY, MEDICINAL)
Yi-Hsien Hsieh, Jen-Pi Tsai, Chen-Lin Yu, Chu-Che Lee, Jen-Chieh Hsu, Jin-Cherng Chen. Overexpression of Lipocalin-2 Inhibits Proliferation and Invasiveness of Human Glioblastoma Multiforme Cells by Activating ERK Targeting Cathepsin D Expression. Biology (Basel). 2021 May 10(5), 390. (2023 IF: 3.6; Q1, 21/109 in BIOLOGY)
Chen-Lin Yu, Yung-Luen Yu, Shun-Fa Yang, Chung-En Hsu, Chia-Liang Lin, Yi-Hsien Hsieh, Hui-Ling Chiou. Praeruptorin A reduces metastasic effect of human hepatocellular carcinoma cells by targeting ERK/MMP1 signaling pathway. Environmental Toxicology. 2021 Apr, 36(4), 540-549. (2023 IF: 4.4; Q1, 72/359 in ENVIRONMENTAL SCIENCES; Q1, 17/106 in TOXICOLOGY)
Shu-Rong Chen Shih-Wei Wang, Yu-Chi Lin, Chen-Lin Yu, Juei-Yu Yen, Yih-Fung Chen, Yuan-Bin Cheng. Additional alkaloids from Zoanthus vietnamensis with neuroprotective and anti-angiogenic effects. Bioorganic chemistry. 2021 Apr, 109, 104700. (2023 IF:4.5; Q1, 76/313, BIOCHEMISTRY & MOLECULAR BIOLOGY; Q1, 7/58 in CHEMISTRY, ORGANIC)
Chen-Lin Yu, Meng-Shih Weng, Wei-Cheng Chen, Kai-Ting Chien, Chih-Wen Chi, Ching-Hu Chung, Chia-Wen Huang, Po-Chuan Wang, Chien-Chih Chen, An-Chi Tsai, Shih-Chia Liu, Shih-Wei Wang. Moscatilin Inhibits Metastatic Behavior of Human Hepatocellular Carcinoma Cells: A Crucial Role of uPA Suppression via Akt/NF-κB-Dependent Pathway. International journal of molecular sciences. 2021 Mar, 22(6), 2930. (2023 IF: 4.9; Q1, 66/313 in BIOCHEMISTRY & MOLECULAR BIOLOGY; Q2, 67/230 in CHEMISTRY, MULTIDISCIPLINARY)
Tung-Wei Hung, Chao-Yang Chu, Chen-Lin Yu, Chu-Che Lee, Li-Sung Hsu, Yong-Syuan Chen, Yi-Hsien Hsieh, Jen-Pi Tsai. Endothelial Cell-Specific Molecule 1 Promotes Endothelial to Mesenchymal Transition in Renal Fibrosis. Toxins. 2020 Aug, 12(8), 506. (2023 IF: 3.9; Q2, 53/173 in FOOD SCIENCE & TECHNOLOGY; Q2, 23/106 in TOXICOLOGY)
Chen-Lin Yu, Shun-Fa Yang, Tung-Wei Hung, Chia-Liang Lin, Yi-Hsien Hsieh and Hui-Ling Chiou. Inhibition of eIF2α dephosphorylation accelerates pterostilbene-induced cell death in human hepatocellular carcinoma cells in an ER stress and autophagy-dependent manner. Cell Death & Disease. 2019 May, 10(6), 418. (2023 IF: 8.1; Q1, 33/205 in CELL BIOLOGY)